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MBCP® Syringe

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Micro & Macroporous Synthetic Bone Graft Substitute

MBCP® Syringe is a synthetic bone graft substitute: MBCP® Technology granules in mixing delivery system, ideal for bone reconstruction.1,6,11,12
This synthetic bone graft substitute in its syringe can be combined with your osteoinductive factor like bone marrow material for bone tissue engineering.5
It is the adapted synthetic bone graft matrix for tissue engineering.5
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MBCP® Technology’s Key Features

Osteoconductive1,2,3,16
Provides a matrix for new bone growth
Macroporosity8,9,10,15,20
Macropores are a network of interconnected spaces that promote the biological infiltration and cellular colonization by osteoblasts and osteoclasts.
Orthopaedics and Maxillofacial:
It is intended for use as a bone graft to fill or reconstruct osseous bone defects or gaps of the skeletal system (e.g. extremities, spine and pelvis, dental) that are not intrinsic to the stability of the bone structure. Osseous defects can occur as a result of a trauma or in surgically created defects.
It can be used with autograft as a bone graft extender.
MBCP® Syringe is available in:
Granules 1-2mm
5cc – 10cc
[1] Passuti – 1989 – “Macroporous Calcium Phosphate Ceramic Performance in Human Spine Fusion” Clinical Orthopaedics
[2] Rodriguez – 2008 – “Five Years Clinical follow-up Bone Regeneration with CaP bone ceramics” Key Engineering Materials
[3] Kolerman – 2012 – “Clinical Radiographic and Histomorphometrical Analysis of Maxillary Sinus Augmentation using Synthetic Bone Substitute” Journal of Oral and Maxillofacial Surgery
[4] Legeros – 2002 – “Properties of Osteoconductive Biomaterials: Calcium Phosphates” – Clinical Orthopedics
[5] Cavagna – 1999 – “Macroporous Calcium Phosphate Ceramic : a prospective study of 106 cases in Lumbar Spinal Fusion” Journal of Long-Rerm Effects of Medical Implants
[6] Rouvillain – 2009 – “Clinical, radiological and histological evaluation of biphasic calcium phosphate bioceramic wedges filling medial high tibial valgisation osteotomies” The Knee
[7] Ransford – 1998 – “Synthetic porous ceramic compared with autograft in scoliosis surgery 341 patient randomised study” The Journal of Bone and Joint Surgery
[8] Daculsi – 2008 – “Effect of sintering process of HA/TCP bioceramics on microstructure, dissolution, cell proliferation and Bone ingrowth” Key Engineering Materials
[9] Miramond – 2014 – “Comparative critical study of commercial calcium phosphate bone substitutes in terms of physico-chemical properties” – Key Engineering Materials
[10] Duan – 2017 – “Variation of bone forming ability with the physicochemical properties of calcium phosphate bone substitutes” – Article on line
[11] Xie – 2006 – “Evaluation of the osteogenesis and biodegradation of porous biphasic ceramic in the human spine, 20 patients” Biomaterials
[12] Pascal–Mousselard – 2006 – “Anterior Cervical Fusion With PEEK Cages: Clinical Results of a Prospective, Comparative, Multicenter and Randomized Study Comparing Iliac Graft and a Macroporous Biphasic Calcium Phosphate” North American Spine Society
[13] Lavallé – 2004 – “Biphasic Ceramic wedge and plate fixation with locked adjustable screws for open wedge tibial osteotomy” Revue de chirurgie orthopédique
[14] Gouin – 1996 – “Clinical applications of calcium phosphate ceramics” SOFCOT teaching supplement
[15] Gauthier – 1998 – “Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth” Biomaterials
[16] Cho – 2011 – “Bioactivity and osteoconductivity of biphasic calcium phosphates” Bioceramics Development and Applications
[17] Nery – 1992 – “Tissue response to biphasic calcium phosphate ceramic with different ratios of HA/TCP in periodontal osseous defects” – Journal of Periodontology
[18] Schaefer – 2011 – “How degradation of calcium phosphate bone substitute materials is influenced by phase composition and porosity” – Advanced Engineering Materials
[19] Daculsi – 2013 – “Clinical studies of anterior cervical fusion with PEEK cages: comparing illiac graft and a Macroporous Biphasic Calcium Phosphate
[20] Legeros – 1988 – “Significance of the porosity and physical chemistry of Calcium Phosphate Ceramics Biodegradation-Bioresorption
[21] Daculsi – 1999 – “Spongious and cortical bone substitution kinetics at the expense of macroporous biphasic calcium phosphate : animal and human evidence” Bioceramics
[22] Changseong – 2014 – “Eight-Year clinical follow-up of sinus grafts with Micro-Macroporous biphasic calcium phosphate granules” Key Engineering Materials
[23] Gouin – 1995 – “Biphasic macroporous calcium phosphate ceramine bone substitute for filling bone defects : a report of 23 cases” Revue de Chirurgie Orthopédique
To read the complete precautions, please refer to the Instructions for Use.
The product must only be handled or implanted by trained qualified physicians having read the instructions for use.
MBCP® is intended for use by surgeons familiar with bone grafting and rigid fixation techniques.
  • ISO 13485:2016 MDSAP
  • Read the instructions for use
  • MBCP® is supplied sterile and CE-marked as a Class III Medical Device according to Directive EEC/93/42
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Not all products are registered or available in every country/region. Please check with Biomatlante representative for availability and further information.

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